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In 3-AR knockout mice, however, no effect was observed with AOD9604 confirming the dependency of its chronic lipolytic action on 3-AR expression, while also suggesting an additional acute mechanism that may operate through a separate pathway
Additionally, the concentration of AOD9604 in the synovial fluid after injection was estimated to be about 0.19 mg/mL, similar to concentrations used in previous GH injection studies in animal models
No study has ever injected it into a person
Fat-loss and metabolic compound comparison Compound 5-Amino-1MQ Mechanism NNMT inhibitor
Nor does short-term oral exposure evidence establish the safety of other routes, formulations, long-term repeated exposure, or independently manufactured materials