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The activation of the GLP-1 receptor communicates fullness to your brain, helping you eat less, while the GIP receptor improves your body's sugar management
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Mechanistically, we demonstrated that ferroptosis in TECs promoted kidney fibrosis via TGF-/Smad signaling and increased the production of various profibrotic factors, such as TGF-, CTGF, PDGFB, and FGF2
For example, in November 2023, the FDA approved Zepbound, a brand name for the drug tripeptide, already sold as Mounjaro, to treat diabetes
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