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To view a copy of this license, visit About this article Cite this article Tarocco, A., Caroccia, N., Morciano, G

Heparan sulfate proteoglycan as a cell-surface endocytosis receptor

Additionally, Vit A significantly reduces intracellular lipid droplet accumulation by activating transcription factor SKN-1, supports mitochondrial membrane integrity, and enhances resistance to oxidative stress, thereby protecting the sperm membrane from peroxidative damage and maintaining intracellular homeostasis [32]

Thus, we have demonstrated that GSH-targeted therapy selectively kills PC cells in an oxidative stress-dependent manner and that the differences in basal ROS level and antioxidant scavenging capacity induced by stratified expression of VRK2 can well account for the heterogeneous sensitivity to GSH inhibition