Animal studies have shown that semaglutide, the active ingredient in Ozempic, can lead to the formation of thyroid tumours, including medullary thyroid carcinoma (MTC)
Their current strategy is to contain near-term expenses while waiting for clearer long-term data and possible price competition (including generics or biosimilars)
Survodutide, a glucagon/GLP-1 dual agonist, met its primary endpoint of histological improvement in MASH at 48 weeks and also demonstrated a statistically significant improvement in fibrosis, a secondary endpoint
This led to higher levels of cyclin D1, a protein crucial for promoting cell proliferation, suggesting a potential pathway for GLP-1RAs to increase risk for PDAC in humans
Before starting any new supplement regimen, it's advisable to consult with a healthcare professional, who can provide guidance based on your specific health needs and conditions
The authors concluded that rates of obesity were higher among people who reported not using cannabis compared to rates among those who used cannabis at least 3 days per week