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Trade-offs: Fluid retention risk (and other contraindications), slower onset (weeks to months), and careful patient selection

If standard measures, such as eating small, bland meals, avoiding high-fat foods , and eating slowly, are not sufficient, talk to your prescriber about anti-nausea medications or dose adjustments

Gut distress is the most frequently reported mild side effect

The lower weight loss in diabetic populations likely reflects differences in baseline metabolic status rather than reduced drug efficacy

Cardiovascular considerations include a small mean increase in heart rate (1-4 beats per minute) noted in clinical trials

Mild burning or tingling under the tongue is normal and indicates the medication is in contact with the mucosal tissue