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Tumor cells can switch from glycolysis to lipid-dependent energy production and also store excess lipids, which provides energy to support their expansion and metastasis (278)

It is generally accepted that in developing neurons each pool covers around 50% of the mitochondria [41]

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Succinylation of PKM2 promotes its transition from a tetramer to a dimer and its entry into the nucleus, subsequently activating the NLRP3/AIM2 inflammasome and exacerbating macrophage pyroptosis and the release of inflammatory factors (IL-1, HMGB1) ( 5.3 From monitoring to remodeling: translational medicine prospects of macrophage exosomes Given the high plasticity of macrophages during the initiation and resolution phases of ARDS inflammation, transforming their exosomes from simple pathological products into clinical diagnostic and therapeutic tools represents a significant breakthrough direction in the field of critical care immunology

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It is sold exclusively as a research tool compound for in vitro laboratory use and is not intended for human consumption