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Studies suggest that these drugs may alter the expression or function of transporters such as multidrug resistance protein 3/2, which is crucial for the secretion of phosphatidylcholine into bilea necessary component for bile salt solubilization

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Common side effects Nausea Vomiting Diarrhea Constipation Fatigue Decreased appetite Gas/burping Abdominal cramping Less common but more serious side effects Gallbladder issues Pancreatitis Severe digestive discomfort Kidney concerns in dehydrated individuals Providers often start patients on low doses to improve tolerability