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It was previously shown that the GLP-1 receptor can control neuronal function in the rat hippocampus by enhancing GABAA signaling through presynaptic and postsynaptic mechanisms (Korol et al., 2015)
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Once a satisfactory length of LCx was exposed, the animal was heparinized (80 IU/kg), and a silastic vessel loop was passed to encircle the vessel
However, the limited follow-up duration of 6 months raised concerns about potential reverse causality, as undetected suicidal ideation and medical conditions might have influenced the choice of particular anti-obesity or anti-diabetic drugs
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