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The capacity for GSH synthesis is insufficient to maintain GSH concentrations when tissues are exposed to certain drugs or their metabolites (e.g., acetaminophen), redox cycling compounds (e.g., menadione), peroxides (e.g., tertbutyl hydroperoxide), X-rays, or ultraviolet radiation

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Ten samples were different from the rest as they were kept for 25-28 hours before processing and freezing

N Engl J Med 2021;385:50315.ArticlePubMed 54