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not only found that LC3 protein expression was down-regulated in SCs in the HG environment, but also observed the appearance of morphologically and structurally abnormal autophagosomes in the cells, suggesting that autophagy is disrupted in SCs (86)
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In breast cancer, the PPP1R1B truncated subtype (t-Darpp) is upregulated in trastuzumab resistant HER2+ breast cancer
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