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Tirzepatide is a GLP-1 receptor agonist and GIP receptor agonist (dual incretin mimetic) that demonstrated 20% or greater weight loss in clinical trials

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Yet pre-existing leptin receptor resistance often persists, creating a physiological environment that actively resists further weight loss

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[PMID: 7776173] PubMed record related to this compound for laboratory literature review

The Fine Print Shed works with various pharmacy partners, but doesnt publicly mention them upfront