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Highly active antiretroviral therapy drug combination induces oxidative stress and mitochondrial dysfunction in immortalized human blood-brain barrier endothelial cells

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Stress response programs in cancer metabolism Hypoxia Cancer cells encounter a series of environmental stressors within the TME, with hypoxia posing a significant threat because of its profound impact on cellular metabolism

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Mechanism of Action FOXO4-DRI blocks the FOXO4p53 interaction in senescent cells

196,197 TMAO contributes to the onset and progression of atherosclerosis by inducing ECs pyroptosis