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Tumor cells from B-cell lymphoma/leukemia patients and -MYC mice, a B-cell lymphoma mouse model, overproduce glutathione
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They act on GLP-1 receptors in the pancreas (insulin secretion, glucagon suppression), hypothalamus (appetite suppression via POMC/NPY pathways), gastric smooth muscle (delayed emptying), and peripheral tissues including adipose and immune cells
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