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The Water Retention Trap This deserves its own section because it drives more unnecessary dose increases and protocol changes than any other single factor

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GLP-1 and glucagon display similar amino acid N-terminal sequences and bind to structurally related receptors, facilitating the development of single-molecule GLP-1R/GCGR co-agonists

Medication adjustments may be necessary in some cases, particularly if patients experience sustained significant heart rate increases

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