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Evidence for involvement of NADPH and not glutathione as the reductant

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Product Overview 5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in NAD+ metabolism and cellular energy regulation

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[66] This mechanism is commonly seen in older hospitalized patients with long-standing illnesses such as infections, heart failure or autoimmune conditions