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For the EUropean Organization for Research and Treatment of Cancer Head and Neck and Lung Cancer Cooperative Groups

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Not during titration

This recommendation was based primarily on preventing hypotension (low blood pressure), and secondarily, on preventing the fishy body odor due to increased excretion of trimethylamine

10.3389/fimmu.2018.00430 Front Immunol

Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Tabe Y, Allen JE, Wang Z, Wencai M, Lee HC, Orlowski R, Sarbassov DD, Neelapu SS, McDonnell T, Miranda RN, Wang M, Kantarjian H, Konopleva M, Davis, RE, Andreeff M