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10.2337/diacare.28.5.1092 23 del CastilloE.MeierR.ChungM.KoestlerD
The clinical value lies in metabolic protection during weight loss: sermorelin offsets the lean muscle loss and metabolic slowdown that typically accompany caloric restriction, while semaglutide handles appetite suppression and glycemic control
No other states require such stringent testing
Some patients see modest early weight loss in this period
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Each phase affects how long the benefits last
