Production of metabolites from amino acids, however, could play an important role in GLP-1 secretion from the colon, as the microbiota can ferment nutrients reaching the distal intestine (mostly colon) and produce metabolites, which may stimulate GLP-1 and PYY secretion [36,37,38]
As Daniel Drucker explained in the companion podcast, that isnt necessary to achieve the GLP-1 mediated suppression of inflammation in the brain
It is important not to discontinue Ozempic without medical guidance, as abrupt cessation may lead to deterioration in glycaemic control
Patients notice more energy, better fasting glucose levels, and smaller waist measurements
Shiwani, H., Clement, N
MorrisGWalkerAJWalderKBerkMMarxWCarvalhoAFet al