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In connective tissues, the peptide stimulates fibroblast proliferation and extracellular matrix synthesis
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Governments looking to reduce the costs of healthcare and boost economic productivity also need to tread carefully when encouraging the use of GLP-1 drugs in people with obesity without addressing the wider socio-economic challenges patients face as well as the problems posed by the rise in ultra-processed food and poor provision of physical exercise facilities
Retatrutide is now being further evaluated in large-scale phase 3 clinical trials under the TRIUMPH program, which includes multiple studies assessing its effects in obesity, overweight with comorbidities, and type 2 diabetes
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