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Semaglutide common side effects include nausea, vomiting, diarrhea, stomach pain, constipation, heartburn, burping, runny nose/sore throat, and headache
Retatrutide achieved up to 24.2% body weight reduction in 48 weeks in Phase 2, and the recently completed Phase 3 TRIUMPH-4 trial pushed that number to an unprecedented 28.7% at 68 weeks
Ovarian function: Early studies suggest GLP-1s may stimulate ovulation and improve endometrial receptivity, which is essential for embryo implantation [Source: Acta Obstetricia et Gynecologica Scandinavica, 2024]
[Accessed 16th April 2026].
Clinical trials demonstrate that most weight reduction occurs over the first six months of treatment, with continued but slower loss thereafter
The nausea may persist for several hours
