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Arthr Res

GLP-1 medications mimic the natural action of the gut hormone glucagon-like peptide-1 (GLP-1), which regulates blood sugar levels and appetite

During low intensity, carnitine supplementation indeed increases fat oxidation and thereby spared muscle glycogen (stored carbohydrates)

And those taking the drugs for 30 months or longer had more than triple the risk

Concluding remarks Although peripheral organs have relatively low GLP-1R expression, GLP-1 medicines exert anti-inflammatory effects through indirect and direct mechanisms involving neural, immune, and vascular crosstalk