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also developed recombinant Lactobacillus plantarum that expresses FomA protein, a critical pathogenic element of F.n , demonstrating its potential in protecting mice from severe IBD induced by F.n through the oral-gut axis by its oral administration to stimulate protective immune responses in the gut (Zhang et al., 2023)
2) the gut microbiota might be not only the pharmacological target, but also the main site of metabolism, resulting in a low oral bioavailability
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These effects suggest potential improvements in muscle quality and composition, which may be particularly relevant for older adults at risk of muscle loss, although studies specifically focused on this population remain limited
Murat Cemal Yalntan at Mimar Sinan Fine Arts University
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