This blog covers a recent Renegade Research Roundtable, two studies reporting on the effects of GLP-1 agonists on people with mast cell activation syndrome (MCAS) and intracranial hypertension, and two major GLP-1 long-COVID trials getting underway
The scale fluctuates daily, but the trend over weeks tells the real story
Nitric oxide and the immune response
For example: Via a transketolase reaction, xyulose 5-phosphate, which is simply an epimer of ribulose 5-phosphate , (a 5-carbon molecule) reacts with ribose 5-phosphate (another 5-carbon molecule) to form glyceraldehyde 3-phosphate (a 3-carbon molecule) and sedoheptulose 7-phosphate (a 7-carbon molecule)
Activating pathways for creation of NADPH has been shown to protect RPE cells from oxidative damage 74 , and our findings indicate that for developing mouse retinas with RP in which all rods have been lost a possible intervention strategy would be to stimulate synthesis of NADPH
Janowitz D, Grabe HJ, Ruhrmann S, Ettelt S, Buhtz F, Hochrein A,