Ross, D.A
Watson REB, Ogden S, Cotterell LF, Bowden JJ, Bastrilles JY, Long SP, Griffiths CEM
Over time, this energy shortfall sets off a cascade of downstream effects: synaptic dysfunction, impaired protein clearance, neuroinflammation, and ultimately the accumulation of amyloid- and tau pathology Importantly, imaging and metabolic studies consistently show that reductions in cerebral glucose metabolism and perfusion precede cognitive symptoms by years, often decades [8]
It was investigated under phase II clinical trials for the treatment of lipodystrophy, but the death of one participant put the trial to a halt
When you are in either internal medicine or family medicine, you have a wider scope
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