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Maeda K, Hatao M

Mitofusin 2 (MFN2) mediates the fusion of mitochondria to increase mROS, functioning as a ferroptosis promoter

Gastrointestinal complications (gastroparesis): GLP-1 medications slow digestion by delaying stomach emptying

& Kassianos, A

Cell viability and ROS and glutathione intracellular content of cells cultured in liquid medium were assessed by flow cytometry analysis of cells stained for 30 min in the dark with 0.025 M calcein-AM (ThermoFisher Scientific, C3099) at room temperature, 50 M Dichlorodihydrofluorescein-diacetate (DCFDA, ThermoFisher Scientific, D399) at 37 C, and 10 M monochlorobimane (ThermoFisher Scientific, M1381MP) at 37 C, respectively

Genes that were upregulated by more than 1.4-fold in response to GSTO1 knockdown showed an enrichment of pathway terms related to lipid synthesis, sterol metabolism and transcriptional repression