With one major caveat
Resveratrol treatment led to a significant amelioration of behavioral, biochemical, molecular, sensory, and neurological deficits via inhibiting oxidative stress, mitochondrial dysfunction, MMP-9 and TNF- expression in a dose dependent manner [10]
This can lead to poor disease control and potentially serious metabolic complications if the issue goes unrecognized for an extended period
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From the perspective of animal experiments, in ApoE / mice expressing human cholesteryl ester transfer protein (hCETP), TMAO derived from L-carnitine levels inversely correlated with aortic lesion size in both the aortic root and thoracic aorta (23)