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It is not the primary, validated mechanism of action for which GHK-Cu is known
Treatment protocols typically involve microneedling followed immediately by GHK-Cu serum application, allowing the peptide to penetrate through the created channels
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doi: 10.3389/fbioe.2021.643722 Summary Keywords antifungal, alginate oligosaccharide, nystatin, Candida spp., biofilm Citation Powell LC, Adams JYM, Quoraishi S, Py C, Oger A, Gazze SA, Francis LW, von Ruhland C, Owens D, Rye PD, Hill KE, Pritchard MF and Thomas DW (2023) Alginate oligosaccharides enhance the antifungal activity of nystatin against candidal biofilms