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FIGURE 2 Patch-clamp studies testing the effects of bath-applied GLP-1 demonstrated that activating the receptor in hippocampal neurons evoked acute membrane potential changes, proving that GLP-1 receptors exist in the hippocampus and can induce acute neuronal changes ( 140 reduced the frequency of miniature inhibitory and excitatory postsynaptic currents (mEPSCs) (mIPSCs) in rat CA1 pyramidal neurons
Dr Kohli has made significant contributions to medical academics and professional education
One is retatrutide, an injectable drug Eli Lilly is developing thats a triple agonist, meaning that in addition to GLP-1 and GIP, it also targets glucagon
10.1016/j.ajhg.2008.01.009 90 LarbiA.KempfJ.PawelecG
