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If you notice lipohypertrophy developing, pause injections in that area for at least 8 weeks to allow the tissue to normalize
These metabolic improvements often persist even after weight loss plateaus, suggesting tirzepatide modifies underlying body composition regulation rather than producing temporary appetite suppression
Gonzlez-Bernal, D
doi: 10.3892/mmr.2020.11670
Natural GLP-1 gets broken down rapidly by an enzyme called DPP-4, usually within minutes
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