The active compound, Epitalon (Ala-Glu-Asp-Gly) , is a synthetic tetrapeptide modeled after the naturally occurring peptide complex Epithalamin
This structural modification improves the peptides stability while preserving its ability to activate the human GHRH receptor. Its core pathway can be summarized as: GHRH receptor activation intracellular cAMP/PKA signaling endogenous GH release downstream IGF-1 and IGFBP-3 signaling Tesamorelin is also the active ingredient in an FDA-approved prescription medication used for one specific indication: reducing excess abdominal fat in adults with HIV-associated lipodystrophy
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Research suggests the copper complex is the bioactive form copper appears essential for most documented biological activities