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Within this intricate setting, numerous signaling pathways orchestrate tumor cell survival, proliferation, angiogenesis, immune suppression, and metastasis
Wang Z, Klipfell E, Bennett BJ, Koeth R, Levison BS, Dugar B, et al
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Multiple therapeutic strategies have been investigated, such as those that directly alter the tumor cells abilities regarding proliferation, differentiation, and apoptosis, which have achieved longer remission time and increased survival rates