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Storage & Handling Store lyophilized powder at 20 C in a tightly closed container and away from light for long-term stability
Return the vial to refrigerated storage promptly
Patients describe it the same way again and again: I lost the weight but now I have all this extra skin. and I did the hard part. That second phrase matters
Of more than 100 compounds synthesized and tested for TGR inhibition (a more thorough description of compound design will form the basis of a future manuscript), the most promising were selected to be extensively characterized in the in vitro and in vivo studies described below
With combined activation (CagriSema) the effect does not add linearly, but supra-additively , which is why the combination has a stronger clinical result than either component alone
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