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Dehydroascorbate reduction

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To prevent the contribution of dilution effects, metabolite data were mean-centered and the intensities of the spectral peaks of each given sample were normalized to the sum of all metabolite concentrations

Notably, at six months, mean GSH levels in erythrocytes, plasma, and lymphocytes had increased by 30-35% in the high-dose group, which was significantly greater than the increases observed in the placebo group

Next, we determined whether sg CBS could affect the TSS pathway activity and GSH generation at different cystine levels