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Andreeff M , Studeny M, Dembinski J, Cabriera-Hansen M, Zompetta C, Champlin R, Marini F, Lang F

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Editing by podcast doctors, show notes and artwork by Brianna Joyner, and original theme composed by Leland Cox and re-composed by Steve Saunders

7 Recent advances and clinical trials for neurodegenerative diseases 7.1 NP-based siRNA delivery for ADs The instability of siRNA therapy in the circulation and the fact that it is unable to reach target cells in the central nervous system (91, 92) because of the BBB poses the biggest hurdle in siRNA therapy

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