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Treatment with the multi-agonists caused a very significant reduction in body weight during the 72-h treatment period, which was more pronounced in mice treated with GLP1/GIP/Glucagon (Fig

The GLP-1s and GIPs approved by the FDA for weight loss are: Saxenda (liraglutide), Wegovy (semaglutide), and Zepbound (tirzepatide)

Carnitine supplementation alleviates oxidative stress during aging, improves recovery from metabolic challenges, and enhances resistance to oxidative toxicity

The once-weekly dosing schedule may help with medication adherence for some patients

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