"But microdosing has not been well studied in clinical trials, and most of the data is anecdotal." She said that when someone asks her about microdosing a GLP-1, she advises that, since it's off-label (meaning not approved by the FDA), carefully monitoring their blood sugar, weight, and symptoms is essential
12 During disease progression, OA chondrocytes produce matrix-degrading enzymes including matrix metalloproteinase 13 (MMP13), which degrades collagen and A disintegrin, and metalloproteinase with thrombospondin motifs-5 (Adamts-5), which targets aggrecan
Supports Natural Detoxification Pathways
They also help slow gastric emptying and support a more sustained GLP-1 response
In a study with an independent cohort, the prevalence of radiographic knee OA was not significantly associated with dietary selenium intake 109
Never discontinue or adjust your medication without consulting your healthcare team, as abrupt changes may affect your glycaemic control or weight management progress