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The cagrilintide research for men and the broader cagrilintide weight loss data point to unique benefits of amylin receptor activation that extend beyond what GLP-1 or GIP agonism provides
In vitro, it upregulates extracellular matrix genes (COL1A1, elastin, decorin) while suppressing inflammatory cytokines
Some vendors are developing such RPA scripts specifically for PA workflows
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Using HRAs Employers that want to avoid covering GLP-1s for weight loss in their general health plans could provide a health reimbursement account (HRA), using pre-tax dollars, to cover a portion of the cost of these medications
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