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Vardanyan GS, Harutyunyan HS, Aghajanov MI, Vardanyan RS

doi: 10.1182/blood-2006-02-003681 202 OpazoC

Furthermore, we found that chronic hypoxia enhanced ceramide catabolism by inducing hypoxia-inducible factor (HIF)-2 and HIF-2-dependent transcriptional activation of alkaline ceramidase 2 (Acer2)

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By improving fatty acid utilisation during exercise, LCLT may also help spare muscle glycogen, allowing for sustained energy during prolonged physical activity

Basic laboratory evaluation is appropriate for patients with persistent or severe fatigue and should include complete blood count, comprehensive metabolic panel, thyroid-stimulating hormone, ferritin/iron studies, and vitamin B12 and vitamin D levels