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In high-fat diet-induced NAFLD murine models, autophagosomes biogenesis was suppressed through both mTOR activation and Atg7 downregulation, resulting in decreased lipophagy that promoted lipid droplets accumulation and lipotoxicity, such as lipid peroxidation, a key determinant of ferroptosis (43)

Patients should take steps to be as hydrated as possible, especially when suffering gastric side effects like vomiting or diarrhea

[10] [11] Another interaction is with thyroid hormones such as levothyroxine

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