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In addition, the NMF levels were increased at 12 weeks compared with placebo-control levels

One prominent study showed that soy oil and MCT oil are among the best options for bioavailability, but other factors, including the surface-to-volume ratio of individual CoQ10 crystals in different solubilized formulations, may have played a role.52 On the stability side, a study pitting 11 CoQ10 products against one another showed that MCT oil slightly outperformed soy oil in keeping a constant CoQ10 concentration over several months.53 However, these were disparate commercial formulations with numerous other variables that could potentially affect stability

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This matters while clinical approval remains uncertain