once-weekly semaglutide in adults with overweight or obesity pubmed 2.4 mg led to significant decreases body weight and fat mass over 12 months while preserving lean mass and improved muscle function in obesity. Weight and fat VisualAbstract: Semaglutide 2.4 mg once

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However, it is generally reserved for patients who are not candidates for surgery or in specific circumstances where surgery needs to be delayed

Semaglutide is well known for its effectiveness in encouraging weight loss