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It is a 46-residue peptide built entirely from D-amino acids in a reversed sequence, a design that confers high resistance to proteolytic degradation while preserving the spatial topology needed to engage its target

The ornithine is condensed by Arg3 with carbamyl phosphate and forms citrulline

Vata D, et al

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doi: 10.1038/onc.2016.252 92 LiuYCaoX