PMID: 41733506 Redox Biol Dysregulated lipids homeostasis disrupts CHAC1-mediated ferroptosis driving fibroblast growth factor receptor tyrosine kinase inhibitor AZD4547 resistance in gastric cancer
) Study #2 As I said, the second study was performed in 2011 by the same group, but with some improvements (IMHO)
Non-canonical glutamate-cysteine ligase activity protects against ferroptosis
DOI Ionescu M, Frohman LA
However, analysis of LDL and VLDL levels revealed high heterogeneity (I 2 = 53.7% and 76.4%, respectively)
Furthermore, research on redox-targeted therapeutic strategies, particularly the application of mitochondria-targeted antioxidants, may provide valuable translational insights and contribute to the development of improved therapeutic approaches not only for HGSOC but also for other ROS-related diseases