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This article shows that unimolecular GLP1/GIP co-agonism corrects obesity and glucose intolerance in obese rodents and non-human primates

doi: 10.1053/j.gastro.2019.11.312 5

guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g

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Its a structural transformation

In the future, the researchers aim to apply new techniques to study the intracellular effects of GLP-1s over days and weeks