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Notably, GLP-1 and GIP/GLP-1 hybrid drugs are now clinically employed for diabetes and obesity, whereas GLP-2 drugs are used in the clinic to treat short bowel syndrome

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This difference may be owed to variations in the diets between the experiments, or by factors such as slight variations in the gut region examined, microbiota composition, site of fermentation, host genotype, host age and various environmental factors

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Filed Under: clinical trials, Drug Discovery, Metabolic disease/endicrinology