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GLP-1 medications are often used in patients with chronic kidney disease, and caution is warranted

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Most cases of weakness are manageable, though certain symptoms require prompt medical evaluation

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Advances in drug delivery systems, including liposomes and nanophytosomes, address low solubility, rapid metabolism, and limited blood brain barrier penetration, thereby improving central nervous system exposure and pharmacodynamic effects, which is essential for clinical translation of several phytochemicals (Moghaddam et al., 2023