Through systematic evaluation of EED impacts on male fertility and transgenerational health, this review aims to address critical knowledge gaps, inform evidence-based environmental and public health policies, and facilitate development of targeted clinical intervention strategies
Triple GIP/GLP-1/glucagon receptor co-agonists The success of dual receptor agonists for the treatment of type 2 diabetes and obesity in clinical trials, including the approval of one such drug by the FDA and EMA (currently only for type 2 diabetes), has prompted the search for new combinatorial approaches
When to Speak with Your GP or Prescriber Open communication with your healthcare team is essential when taking multiple medications that affect weight, appetite, and metabolism
Discuss your specific needs with a healthcare provider familiar with your history
When medication is reduced or stopped, appetite may return
In SURPASS-2, a head-to-head in T2D patients, tirzepatide 15 mg produced 11.2 kg weight loss versus 5.7 kg on semaglutide 1 mg (the T2D dose at the time, not the 2.4 mg obesity dose)