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Choline an essential nutrient required for phosphatidylcholine synthesis, which is genuinely necessary for VLDL assembly and hepatic fat export
However, more studies are needed to understand its effects fully
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In a 26-week rat oral toxicity study, AOD-9604 produced dose-dependent changes in serum osteocalcin (a bone-turnover marker) at week 13, with the direction reversing by week 26
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