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The SmPC notes that rapid improvement in glucose control has been associated with temporary worsening of diabetic retinopathy, particularly in patients with pre-existing retinopathy

To better isolate a true Type 1 diabetic population, they excluded individuals with Type 2 diabetes and those taking sodiumglucose cotransporter-2 (SGLT2) inhibitors

The mean absolute bioavailability of Tirzepatide following subcutaneous administration is 80% (source)

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The specific mechanisms by which these plants may protect tissues from drug toxicity, exert antioxidant effects, regulate immune function, and control thyroxine levels remain largely unexplored

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