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Glp-1ra therapy increases circulating vascular regenerative cell content in people living with type 2 diabetes

The intake level of dietary Met could affect the lipid and bile acid metabolism in the liver in mice, and Met-restricted diet could restore the normal bile acid pool in the liver (82)

However, approximately 10-15% of users report persistent loose stools beyond three months, suggesting that some individuals have a longer adaptation window or heightened intestinal sensitivity

Newer diabetes medications like GLP-1 receptor agonists (Ozempic, Mounjaro) seem to promote the most weight loss, while oral drugs like metformin and SGLT2 Inhibitors (Jardiance) tend to lead to more modest outcomes for weight

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Saunders PT, Horne AW